The Guardians of the Galaxy Set is an expansion for Marvel Zombies that introduces a roster of space-dwelling characters to the game, including the ragtag members of the Guardians of the Galaxy. This band of living and zombie heroes must all contend with the momentous threat of zombie Thanos, as he wields the Infinity Stones to carry out his mad plan!

Thanos acts as a special Enemy spawn that can be used with any mission, whether it be in Zombie Mode or Hero Mode. Every time Thanos activates, he taps into the power of one of the stones (represented by a special Action deck). This will gives him additional game-altering effects during that Activation.